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darkoz
darkoz
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May 9th, 2020 at 2:21:08 PM permalink
Quote: mcallister3200

7 out of 54 doesn’t really sound promising at all to me almost 13% of patients died. Can interpret than any way you choose I suppose. I read the article it didn’t really seem to say much, read more like an advertisement puff piece than a review with the way terminology was used, lifting 2-3 word partial quotes without providing any context. What context was provided seemed to believe it saved 4 lives that otherwise could have passed. Hopefully I’m wrong there! Article also seemed to say 49 rather than 54 unless I missed something, maybe another 23 elsewhere?



They state at the end five new people have just been placed into the program so I said 54. Plus this is already a week old so I know from other articles it's 54.

As to percentage I think Remdesvir which has been getting a lot of attention recently had a 37% death rate.

Leronlimab is currently doing spectacular compared to the other drugs in testing
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billryan
billryan
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May 9th, 2020 at 2:46:34 PM permalink
They've now done at least a half dozen legitimate studies on hydrowhatever and in none of them were any miracle cures noted. What are we supposed to make of the people who were claiming incredible results?
How many million doses did taxpayers pay for?

Incredibly, 45% of the US population isn't sure they will get a vaccine when it becomes available. Roughly 25% say they won't get it and another 20% are not sure.
darkoz
darkoz
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May 9th, 2020 at 2:56:22 PM permalink
Quote: billryan

They've now done at least a half dozen legitimate studies on hydrowhatever and in none of them were any miracle cures noted. What are we supposed to make of the people who were claiming incredible results?
How many million doses did taxpayers pay for?

Incredibly, 45% of the US population isn't sure they will get a vaccine when it becomes available. Roughly 25% say they won't get it and another 20% are not sure.



I agree.

Hydroxychloriquine was a joke pushed by non-scienctific facts and now proven a waste.

Leronlimab is currently in two clinical trials.

Mild/moderate patients with 75 enrolled

Severely critical patients with 390 enrolled in a 2:1 placebo double blind study.

Once the studies are done we will have definitive proof as to the efficacy of Leronlimab

As to safety that has already been shown in a previous HIV enrollment in which no side effects occurred

Safety and efficacy coming for Leronlimab

This will reopen the economy
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gordonm888
gordonm888
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May 9th, 2020 at 5:15:32 PM permalink
I am hoping for Leronlimnab to be everything we need.

I too was a bit underwhelmed by the 7 reported deaths, but then I read that a large number of the patients in this trial were in critical condition. The article claims that 4 (maybe 5) lives have been saved already. That's encouraging.
So many better men, a few of them friends, were dead. And a thousand thousand slimy things lived on, and so did I.
darkoz
darkoz
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May 9th, 2020 at 5:43:57 PM permalink
Quote: gordonm888

I am hoping for Leronlimnab to be everything we need.

I too was a bit underwhelmed by the 7 reported deaths, but then I read that a large number of the patients in this trial were in critical condition. The article claims that 4 (maybe 5) lives have been saved already. That's encouraging.



Let me be a bit clear on Leronlimab vs Remdesvir

Remdesvir is an intravenous treatment only so even if Remdesvir is a successful treatment it will only be administered to hospitalized patients

If you have symptoms that doesn't require a hospital stay then you will just be sent home until you get sicker.

Leronlimab is two simultaneous injections followed by a second two one week later.

That's it!

This is huge. It means anyone suffering even mild symptoms would be treated immediately and sent home BEFORE they become seriously ill.

And it seems to save some percentage of those deathly ill.

While having a 100% success at avoiding death for those seriously ill but not yet critically (hospitalized but not on ventilators)

That's why there are currently two FDA clinical trials ongoing. One for mild/moderate patients and one for critically ill. Even the FDA sees the potential

This is the game changer.
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billryan
billryan
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May 9th, 2020 at 6:01:38 PM permalink
Quote: darkoz

Let me be a bit clear on Leronlimab vs Remdesvir

Remdesvir is an intravenous treatment only so even if Remdesvir is a successful treatment it will only be administered to hospitalized patients

If you have symptoms that doesn't require a hospital stay then you will just be sent home until you get sicker.

Leronlimab is two simultaneous injections followed by a second two one week later.

That's it!

This is huge. It means anyone suffering even mild symptoms would be treated immediately and sent home BEFORE they become seriously ill.

And it seems to save some percentage of those deathly ill.

That sounds wildly optimistic.

While having a 100% success at avoiding death for those seriously ill but not yet critically (hospitalized but not on ventilators)

That's why there are currently two FDA clinical trials ongoing. One for mild/moderate patients and one for critically ill. Even the FDA sees the potential

This is the game changer.

darkoz
darkoz
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May 9th, 2020 at 6:20:36 PM permalink
Quote: billryan



Why does it sound wildly optimistic?

I am optimistic about it but based on my research

I wouldn't classify it as "wildly"

It is under clinical trials so yeah it could still fail. That's the point of the trials.

But this is looking good to me so far
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AxelWolf
AxelWolf
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May 9th, 2020 at 6:45:25 PM permalink
Quote: darkoz

Why does it sound wildly optimistic?

I am optimistic about it but based on my research

I wouldn't classify it as "wildly"

It is under clinical trials so yeah it could still fail. That's the point of the trials.

But this is looking good to me so far

Fool me once, shame on you, fool me twice shame on me.

I'm pretty cynical/ skeptical, basically I'll believe it when they're actually using it on a mass scale.
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mcallister3200
mcallister3200
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Thanks for this post from:
Minty
May 9th, 2020 at 6:57:30 PM permalink
Quote: darkoz

Why does it sound wildly optimistic?

I am optimistic about it but based on my research

I wouldn't classify it as "wildly"

It is under clinical trials so yeah it could still fail. That's the point of the trials.

But this is looking good to me so far



It sounds wildly optimistic because the terminology you are using states it is as a certainty or a guarantee rather than hopefulness or simply confidence. “WHEN this is approved”, “this IS a game changer,” “this WILL reopen the economy,” etc rather than “if,” or “could be,” etc.
darkoz
darkoz
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May 9th, 2020 at 7:02:46 PM permalink
Quote: mcallister3200

It sounds wildly optimistic because the terminology you are stating it is as a certainty or a guarantee rather than hopefulness or simply confidence. “WHEN this is approved”, “this IS a game changer,” “this WILL reopen the economy,” etc rather than “if,” or “could be,” etc.



Okay Perhaps I am wildly optimistic!!!

But it's based on weeks of research I have been putting into this specific drug.

While I am not a medical person I have read the medical science behind the drug and the published layman explanations.

It sounds much more real than any of the other drugs currently in development.

Let me put it this way. I am not a betting man on stuff like this usually but on Leronlimab I am wagering
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